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Journal of the Korean Society of Pediatric Nephrology 2008;12(2): 221-226. doi: http://dx.doi.org/10.3339/jkspn.2008.12.2.221
급성 신부전을 동반한 발작 야간 혈색소뇨증 2례
류정민, 안요한, 이소희, 최현진, 이범희, 강희경, 강형진, 신희영, 하일수, 정해일, 안효섭, 최용
1서울대학교 어린이병원 소아청소년과
2서울대학교 어린이병원 소아청소년과
3서울대학교 어린이병원 소아청소년과
4서울대학교 어린이병원 소아청소년과
5서울대학교 어린이병원 소아청소년과
6서울대학교 어린이병원 소아청소년과
7서울대학교 어린이병원 소아청소년과
8서울대학교 어린이병원 소아청소년과
9서울대학교 어린이병원 소아청소년과
10서울대학교 어린이병원 소아청소년과
11서울대학교 어린이병원 소아청소년과
12서울대학교 어린이병원 소아청소년과
Two Cases of Acute Renal Failure Complicating Paroxysmal Nocturnal Hemoglobinuria in Children
Jung-Min Ryu, Yo-Han Ahn, So-Hee Lee, Hyun-Jin Choi, Beom-Hee Lee, Hee-Gyung Kang, Hyoung-Jin Kang, Hee-Young Shin, Il-Soo Ha, Hae-Il Cheong, Hyo-Seop Ahn, Yong Choi
1Department of Pediatrics, Seoul National University Childrens Hospital
2Department of Pediatrics, Seoul National University Childrens Hospital
3Department of Pediatrics, Seoul National University Childrens Hospital
4Department of Pediatrics, Seoul National University Childrens Hospital
5Department of Pediatrics, Seoul National University Childrens Hospital
6Department of Pediatrics, Seoul National University Childrens Hospital
7Department of Pediatrics, Seoul National University Childrens Hospital
8Department of Pediatrics, Seoul National University Childrens Hospital
9Department of Pediatrics, Seoul National University Childrens Hospital
10Department of Pediatrics, Seoul National University Childrens Hospital
11Department of Pediatrics, Seoul National University Childrens Hospital
12Department of Pediatrics, Seoul National University Childrens Hospital
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ABSTRACT
Paroxysmal nocturnal hemoglobinuria(PNH) is an acquired hematologic disorder characterized by intravascular hemolysis, nocturnal hemoglobinuria, thrombotic events and bone marrow failure. It rarely occurs in children and can be complicated by acute renal failure(ARF). Here, we present two cases of ARF complicating PNH which has not been reported yet in Korean children. We suggest that PNH should be considered in differential diagnosis of ARF in children associated with intravascular hemolysis.
Key words: Paroxysmal nocturnal hemoglobinuria(PNH) | Acute renal failure | Intravascular hemolysis | Children
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