No Effect of IV cyclophosphamide in Children with Steroid Resistant Nephrotic Syndrome

Min, Su-Jeen; Lee, Chang-Yeun

J Korean Soc Pediatr Nephrol > Volume 2(2); 1998 > Article

J Korean Soc Pediatr Nephrol 1998;2(2): 183-186.

스테로이드 저항성 신증후군 소아 3례에서 Cyclophosphamide 정맥투여요법의 치료실패

민수진, 이창연

¹고신대학 복음병원 소아과학 교실
²고신대학 복음병원 소아과학 교실

No Effect of IV cyclophosphamide in Children with Steroid Resistant Nephrotic Syndrome

Su-Jeen Min, Chang-Yeun Lee

¹Department of Pediatrics, Kosin Medical College
²Department of Pediatrics, Kosin Medical College

ABSTRACT

Steroid Resistant Nephrotic Syndrome(SRNS) in children has poor prognosis and no effective therapy. In 1994, Ravi Elhence have reported that IV cyclophosphamide therapy was effective against SRNS of children. So, we evaluated the efficacy of IV cyclophosphamide in 3 children with biopsy proven steroid-resistant MCNS. And the result was the rapeutic failure. In conclusion, IV cyclophosphamide therapy wass not effective against SRNS of children.

Key words: IV cyclophosphamide | SRNS