Clinical Manifestations of Ureteral Duplication in Children

Han, Jung-Woo; Hwang, Dae-Hwan; Park, Jee-Min; Han, Sang-Won; Lee, Jae-Seung

J Korean Soc Pediatr Nephrol > Volume 7(2); 2003 > Article

J Korean Soc Pediatr Nephrol 2003;7(2): 189-196.

소아 중복 요관의 임상적 고찰

한정우, 황대환, 박지민, 한상원, 이재승

¹연세대학교 의과대학 소아과학교실, 신장질환연구소
²연세대학교 의과대학 소아과학교실, 신장질환연구소
³연세대학교 의과대학 소아과학교실, 신장질환연구소
⁴연세대학교 의과대학 비뇨기과학교실
⁵연세대학교 의과대학 소아과학교실, 신장질환연구소

Clinical Manifestations of Ureteral Duplication in Children

Jung-Woo Han, Dae-Hwan Hwang, Jee-Min Park, Sang-Won Han, Jae-Seung Lee

¹Department of Pediatrics, The Institute of Kidney Disease, Yonsei University, College of Medicine
²Department of Pediatrics, The Institute of Kidney Disease, Yonsei University, College of Medicine
³Department of Pediatrics, The Institute of Kidney Disease, Yonsei University, College of Medicine
⁴Departments of Urology, Yonsei University, College of Medicine
⁵Department of Pediatrics, The Institute of Kidney Disease, Yonsei University, College of Medicine

ABSTRACT

Purpose : Ureteral duplication is a common urologic anomaly and early diagnosis may prevent irreversible renal damage. We thus aimed to evaluate the benefits of prenatal sonography in early detection.
Methods : We retrospectively studied 55 children with duplicated systems who were admitted to Severance Hospital, Yonsei University, Seoul, Korea from January 1998 to July 2003.
Results : The mean age at diagnosis was 2.3 years old. 89% of the children had complete duplicated ureter. 47% of the children visited the hospital with an initial complaint of abnormal prenatal sonographic findings. Among these patients, 70.8% had DMSA defects. The mean differential renal function(DRF) in the DMSA scan was 48.2% in the group diagnosed prenatally. In the postnatally-diagnosed group, DMSA defects were found in 67.7% patients and the mean DRF was 45.5%.
Conclusion : In comparison with the past studies, the mean age at diagnosis is becoming younger, and the proportion of abnormal prenatal sonography as an initial complaint larger. Other clinical manifestations were similar. The difference of the renal damage between the prenatally diagnosed group and the postnatally diagnosed group was not statistically significant. A multi-center study may help to prove the importance of prenatal sonography in early diagnosis and treatment of ureteral duplication.

Key words: Ureteral duplication | Prenatal sonography | Antenatal care