| Home | E-Submission | Sitemap | Contact Us |  
Journal of the Korean Society of Pediatric Nephrology 2003;7(2): 245-252.
소아에서 신장 이식 후 발생한 Posttransplant Lymphoproliferative Disease 1례
장원경, 한혜원, 이미정, 김태형, 박영서
1울산대학교 의과대학 서울아산병원 소아과
2울산대학교 의과대학 서울아산병원 소아과
3울산대학교 의과대학 서울아산병원 소아과
4울산대학교 의과대학 서울아산병원 소아과
5울산대학교 의과대학 서울아산병원 소아과
A Case of Posttransplant Lymphoproliferative Disease Following Renal Transplantation in a Child
Won-Kyoung Jhang, Hye-Won Hahn, Mee-Jeung Lee, Thad-T. Ghim, Young-Seo Park
1Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center
2Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center
3Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center
4Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center
5Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center
Share :  
ABSTRACT
Posttransplant lymphoproliferative disease(PTLD) has emerged as a potential life-threatening complication of immunosuppressive therapy after organ transplantation. The occurrence of PTLD is usually associated with an Epstein-Barr virus(EBV) infection in patients who are treated by aggressive immunosuppressive therapy. PTLD is represented by diverse manifestations ranging from reactive lymphoid hyperplasia to high grade malignant lymphoma. This is a case report of a late PTLD in a child. The patient is a 14-year-old girl, who presented as malignant lymphoma 44 months after successful renal transplantation. There was no evidence of EBV infection. On bone marrow study, many neoplastic lymphoid cells were defected. Aggressive chemotherapy for PTLD had resulted in clinical remission. However the patient expired from uncontrolled sepsis and septic shock after 77 days.
Key words: Posttransplant lymphoproliferative disease | EBV | Late-onset | Malignant lymphoma | Kidney transplantation
Editorial Office
124 Bukbyunjeung-ro, Kimpo, Jesewoong 2-103, Gyeonggi-do 10098, Republic of Korea
TEL : +82-31-987-5963   FAX : +82-31-987-5967   E-mail : chikd.editor@gmail.com or ckdeditor@kspn.org

Copyright© Korean Society of Pediatric Nephrology. All rights reserved.                powerd by m2community
About |  Browse Articles |  Current Issue |  For Authors and Reviewers