A Case of Diabetic Nephropathy in a Child with Type 1 Diabetes

Jung, Hwan-Hee; Park, Sung-Sin; Kim, Sung-Do; Cho, Byoung-Soo

doi:2008.12.2.250

J Korean Soc Pediatr Nephrol > Volume 12(2); 2008 > Article

J Korean Soc Pediatr Nephrol 2008;12(2): 250-255. doi: https://doi.org/10.3339/jkspn.2008.12.2.250

제 1형 당뇨병 소아환자에서 발생한 당뇨병성 신병증 1례

정환희, 박성신, 김성도, 조병수

¹경희대학교 의과대학 소아청소년과학교실
²경희대학교 의과대학 소아청소년과학교실
³경희대학교 의과대학 소아청소년과학교실
⁴경희대학교 의과대학 소아청소년과학교실

A Case of Diabetic Nephropathy in a Child with Type 1 Diabetes

Hwan-Hee Jung, Sung-Sin Park, Sung-Do Kim, Byoung-Soo Cho

¹Department of Pediatrics, College of Medicine, Kyunghee University
²Department of Pediatrics, College of Medicine, Kyunghee University
³Department of Pediatrics, College of Medicine, Kyunghee University
⁴Department of Pediatrics, College of Medicine, Kyunghee University

ABSTRACT

Diabetes mellitus(DM) is a metabolic syndrome caused by deficiency of insulin secretion and a consequence of insulin resistance. Poor glycemic control is a common finding in children with Type 1 DM(T1DM). Approximately 60% of the young patients with T1DM develop abnormalities in the eyes and 15-20% in the kidney. Diabetic nephropathy (DN) is a serious metabolic complication of T1DM that leads to renal failure. Some clinical studies report that the duration of prepubertal diabetes may contribute less to the development of microvascular complications than pubertal and postpubertal duration. There have been few cases of DN in prepubertal patients with T1DM in Korea. Thus we report a case of a 12-year-old female with T1DM who had poor glycemic control and was diagnosed as DN in a prepubertal period. It was proven by renal biopsy after microscopic hematuria and proteinuria were detected through the mass school urinary screening program.

Key words: Diabetic nephropathy | Children | Type 1 DM | Prepubertal duration