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Journal of the Korean Society of Pediatric Nephrology 2010;14(1): 1-9. doi: https://doi.org/10.3339/jkspn.2010.14.1.1
소아 청소년 만성 콩팥병의 진행 억제
하일수, 최용
1서울대학교 어린이병원 소아청소년과, 서울대학교 의과대학 의학연구원 신장연구소
2인제대학교 해운대백병원 소아청소년과
Slowing the Progression of Chronic Kidney Disease in Children and Adolescents
Il-Soo Ha, Yong Choi
1Department of Pediatrics, Seoul National University Children's Hospital Kidney Institute, Seoul National University Medical Research Center
2Department of Pediatrics, Inje University Haeundae Paik Hospital
Received: April 5, 2010;  Revised: April 10, 2010.  Accepted: April 20, 2010.
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ABSTRACT
Slowing the progression of chronic kidney disease is much more important in children and adolescents with a relatively longer remaining life span. A practical way to assess the rate of progression of chronic kidney disease is to measure the change of GFR estimated by formulae. To slow the progression, hypertension and proteinuria have to be controlled strictly, and hypoplastic anemia must be treated with erythropoietin. If not contraindicated, ACE inhibitor or angiotensin receptor blocker is recommended with monitoring of the side effects. Trials to slow the progression should be commenced as soon as the chronic kidney disease is confirmed and needs to be continued until renal transplantation as long as residual renal function remains. An online system, the Korean Pediatric Chronic Kidney Disease Registry (http://pedcrf.or.kr/), provides tools that are useful in evaluation and management of the children and adolescents with chronic kidney diseases.
Key words: Chronic kidney disease | Progression | Children | Adolescents
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