ABO 부적합 신이식 후 발생한 용혈 1례 |
한혜원, 하일수, 정해일, 최용 |
1서울대학교 의과대학 소아과학교실 2서울대학교 의과대학 소아과학교실 3서울대학교 의과대학 소아과학교실 4서울대학교 의과대학 소아과학교실 |
A Case of Hemolysis after Minor ABO Mismatched Kidney Transplantation |
HyeWon Hahn, Il Soo Ha, Hae Il Cheong, Yong Choi |
1Department of pediatrics, Seoul National University College of Medicine 2Department of pediatrics, Seoul National University College of Medicine 3Department of pediatrics, Seoul National University College of Medicine 4Department of pediatrics, Seoul National University College of Medicine |
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ABSTRACT |
A 9-year-old boy of B blood group with end-stage renal disease due to IgA nephropathy received group O kidney transplantation from his father. On day 9, he developed intravascular hemolysis, and anti-B autoantibody formation was confirmed. We diagnosed as immune hemolytic anemia due to passenger lymphocyte from donor, and cyclosporine withdrawl was done. Anemia resolved spontaneously, but on day 18, graft dysfunction developed, and graft biopsy revealed acute allograft rejection. Although hemolysis due to autoantibody is very rare and often mild, and the role of hemoglobinuria on acute rejection in this case is not certain, we recommend consideration of aggressive management on severe hemolysis after minor mismatched kidney transplantation. |
Key words:
Hemolysis | ABO mismatched kidney transplatation | Autoantibody |
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