J Korean Soc Pediatr Nephrol > Volume 7(2); 2003 > Article
Journal of the Korean Society of Pediatric Nephrology 2003;7(2): 142-149.
학교 신체 검사에서 발견된 단독 단백뇨의 분석
오동환, 김정수, 박지경, 정우영
1광혜병원
2인제대학교 의과대학 부산백병원 소아과
3인제대학교 의과대학 부산백병원 소아과
4인제대학교 의과대학 부산백병원 소아과
Analysis of Isolated Proteinuria on School Urinary Mass Screening Test in Busan and Kyungsangnam-do Province
Dong-Hwan Oh, Jung-Soo Kim, Ji-Kyoung Park, Woo-Yeong Chung
1Kwang Hye General Hospital
2Deportment of Pediatrics, College of Medicine, Inje University, Busan Paik Hospital
3Deportment of Pediatrics, College of Medicine, Inje University, Busan Paik Hospital
4Deportment of Pediatrics, College of Medicine, Inje University, Busan Paik Hospital
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ABSTRACT
Purpose : The urinary mass screening program for the detection of urinary abnormalities in school aged population has been performed in Seoul since 1981. Nation-wide urinary mass screening program was also performed since 1998. The aim of this study was to analyze the cause and nature of isolated proteinuria detected by chance on the urinary mass screening test in Busan and Kyungsangnam-do Province
Methods : The medical records of 44 cases of isolated proteinuria detected by chance on the urinary mass screening test in Busan and Kyungsangnam-do Province, and evaluated for urinary abnormalities at the pediatrics outpatients renal clinics of Busan Paik Hospital from April 2002 to August 2003 were reviewed prospectively.
Results : The cause and incidence of isolated proteinuria were as follows; transient proteinuria 4 cases(9.1%), orthostatic proteinuria 36 cases(81.8%) and persistent proteinuria 4 cases (9.1%). The total protein amount of the 24 hour urine were $121.0{pm}136.4;mg$ in transient proteinuria, $179.1{pm}130.0;mg$ in orthostatic proteinuria and $1532.8{pm}982.5;mg$ in persistent proteinuria. In the orthostatic proteinuria group, the total protein amount of the 24 hour urine was in the range of 40-616 mg. Spot urine protein/creatinine ratio(PCR) were $0.10{pm}0.01$ in transient proteinuria, $0.61{pm}0.61$ in orthostatic proteinuria and $4.35{pm}4.04$ in persistent proteinuria. In the orthostatic proteinuria group, spot me PCR was in the range of 0.09-2.32. Renal biopsy was peformed in 4 children of the persisitent proteinuria group. They showed minimal change in 1 case, membranoproliferatiye glomerulonephritis in 2 cases and secondary renal amyloidosis in 1 case.
Conclusion : The majority of isolated proteinuria which was detected by chance on school urinary mass screening were transient or orthostatic proteinuria. Even though the incidence of persistent proteinuria was much lower, it is necessary to take care of these children regularly and continuously, because persistent proteinuria itself is a useful marker of the progressive renal problems.
Key words: Isolated proteinuria | School urinary mass screening test
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