Outcomes of Chronic Peritoneal Dialysis by Various Modalities in Korean Children - A Single Center Study

Lee, Sung-Ha; Baek, Jae-Suk; Lee, Hyun-Kyung; Han, Kyoung-Hee; Choi, Hyun-Jin; Lee, Bum-Hee; Cho, Hee-Yeon; Cheong, Hae-Il; Choi, Yong; Ha, Il-Soo

doi:2007.11.2.255

J Korean Soc Pediatr Nephrol > Volume 11(2); 2007 > Article

J Korean Soc Pediatr Nephrol 2007;11(2): 255-263. doi: https://doi.org/10.3339/jkspn.2007.11.2.255

소아 환자에서 다양한 복막투석 방법간의 결과 비교-단일기관 연구

이성하, 백재숙, 이현경, 한경희, 최현진, 이범희, 조희연, 정해일, 최용, 하일수

¹서울대학교 의과대학 소아과학교실
²서울대학교 의과대학 소아과학교실
³서울대학교 의과대학 소아과학교실
⁴서울대학교 의과대학 소아과학교실
⁵서울대학교 의과대학 소아과학교실
⁶서울대학교 의과대학 소아과학교실
⁷
⁸서울대학교 의과대학 소아과학교실
⁹서울대학교 의과대학 소아과학교실
¹⁰서울대학교 의과대학 소아과학교실

Outcomes of Chronic Peritoneal Dialysis by Various Modalities in Korean Children - A Single Center Study

Sung-Ha Lee, Jae-Suk Baek, Hyun-Kyung Lee, Kyoung-Hee Han, Hyun-Jin Choi, Bum-Hee Lee, Hee-Yeon Cho, Hae-Il Cheong, Yong Choi, Il-Soo Ha

¹Department of Pediatrics, Seoul National University College of Medicine
²Department of Pediatrics, Seoul National University College of Medicine
³Department of Pediatrics, Seoul National University College of Medicine
⁴Department of Pediatrics, Seoul National University College of Medicine
⁵Department of Pediatrics, Seoul National University College of Medicine
⁶Department of Pediatrics, Seoul National University College of Medicine
⁷Department of Pediatrics, Gachon University Gil Medical Center
⁸Department of Pediatrics, Seoul National University College of Medicine
⁹Department of Pediatrics, Seoul National University College of Medicine
¹⁰Department of Pediatrics, Seoul National University College of Medicine

ABSTRACT

Purpose : A single center cross sectional retrospective study was performed to compare the outcomes of different peritoneal dialysis(PD) modalities in Korean children.
Methods : Among children dialyzed with PD between the year 2004 and 2007, 35 children had reliable data on PD adequacy after 3 to 15 months of dialysis. Subjects were grouped by their modalities; 17, 13 and 5 children were on continuous ambulatory PD(CAPD), continuous cyclic PD(CCPD) and nightly intermittent PD(NIPD), respectively. Body weight and height, number of patients taking anti-hypertensives and laboratory data including biochemical and hemoglobin levels were compared. Dialysis adequacy including weekly Kt/Vurea, creatinine clearance (Ccr) and daily water removal were also compared. Patients were sub-grouped by their peritoneal permeability characteristics.
Results : The percentage of patients taking anti-hypertensives, monthly change in Z-scores of body weight and height and laboratory data did not differ among the groups. Patients on CAPD and CCPD showed similar dialysis adequacies. Weekly dialytic Ccr was significantly lower in the NIPD group compared to the others. But total Ccr was not different when residual renal function was added. Weekly dialytic Ccr by CAPD was significantly higher than that of CCPD in low and low-average transporters.
Conclusion : We propose that modality can be selected flexibly according to the patients' preferences. And peritoneal permeability characteristics provide valuable information for adjusting PD prescriptions in ultrafiltration failure or in inadequate dialysis. Further study of other clinical performance measures should be performed to clarify the comparable outcomes in different PD modalities.