A Case of Acute Renal Failure due to Rhabdomyolysis Associated with Neuroleptic Malignant Syndrome

Park, Kyu-Hee; Jung, Seong-Kwan; Yim, Hyung-Eun; Yoo, Kee-Hwan; Hong, Young-Sook; Lee, Joo-Won

doi:2009.13.2.267

J Korean Soc Pediatr Nephrol > Volume 13(2); 2009 > Article

J Korean Soc Pediatr Nephrol 2009;13(2): 267-270. doi: https://doi.org/10.3339/jkspn.2009.13.2.267

항정신병약물악성증후군에 동반한 횡문근융해증으로 인한 급성 신부전 1례

박규희, 정성관, 임형은, 유기환, 홍영숙, 이주원

¹고려대학교 의과대학 소아과학교실
²고려대학교 의과대학 소아과학교실
³고려대학교 의과대학 소아과학교실
⁴고려대학교 의과대학 소아과학교실
⁵고려대학교 의과대학 소아과학교실
⁶고려대학교 의과대학 소아과학교실

A Case of Acute Renal Failure due to Rhabdomyolysis Associated with Neuroleptic Malignant Syndrome

Kyu-Hee Park, Seong-Kwan Jung, Hyung-Eun Yim, Kee-Hwan Yoo, Young-Sook Hong, Joo-Won Lee

¹Department of Pediatrics, College of Medicine, Korea University
²Department of Pediatrics, College of Medicine, Korea University
³Department of Pediatrics, College of Medicine, Korea University
⁴Department of Pediatrics, College of Medicine, Korea University
⁵Department of Pediatrics, College of Medicine, Korea University
⁶Department of Pediatrics, College of Medicine, Korea University

ABSTRACT

Neuroleptic malignant syndrome (NMS) is a rare, but a potentially life threatening condition associated with the use of antipsychotics. The most frequent signs and symptoms of NMS include fever, muscle rigidity, autonomic dysfunction such as tachycardia, tachypnea, and labile blood pressure. Acute complications of NMS include disseminated intravascular coagulation, sepsis, seizure, myocardial infarction, acute renal failure due to rhabdomyolysis and death. We report a rare case of acute renal failure due to rhabdomyolysis associated with neuroleptic malignant syndrome.

Key words: Neuroleptic malignant syndrome | Rhabdomyolysis | Acute renal failure