J Korean Soc Pediatr Nephrol > Volume 15(1); 2011 > Article
Journal of the Korean Society of Pediatric Nephrology 2011;15(1): 22-28. doi: https://doi.org/10.3339/jkspn.2011.15.1.22
중추신경계에 미치는 소아 고혈압의 영향
허윤정
인제대학교 해운대 백병원 소아과학교실
The Effect of Systemic Hypertension on the Pediatric Brain
Yun-Jung Hur
Department of Pediatrics, Haeundae Paik Hospital, Inje University College of Medicine
Received: March 16, 2011;  Accepted: March 31, 2011.
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ABSTRACT
Hypertension is one of the most common chronic diseases in childhood and adolescence. Untreated hypertension adversely affects many organs including heart, brain, kidney and peripheral arteries. We reviewed the complication of central nervous system caused by pediatric hypertension. Cerebral blood flows are maintained constantly in response to changes in blood pressure by cerebral autoregulation. Severe hypertension which destructs cerebral autoregulation results in acute hypertensive encephalopathy syndrome, ischemic or hemorrhagic stroke. Chronic pediatric hypertension induces learning disability and cognitive defect which are subclinical symptom prior to brain damage caused by severe hypertension. We should consider the effect of hypertension on pediatric brain because appropriate antihypertensive drugs could prevent these complications.
Key words: Hypertension | Hypertensive encephalopathy | Stroke | Communication disorders
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