Three Cases of Erythema Multiforme Developed during Deflazacort Therapy in Children with Nephrotic Syndrome

Lee, Seung Jin; Kang, Bong Hwa; Cho, Min Hyun

doi:2014.18.2.123

Child Kidney Dis > Volume 18(2); 2014 > Article

Case Report

J Korean Soc Pediatr Nephrol 2014;18(2): 123-127. doi: https://doi.org/10.3339/jkspn.2014.18.2.123

Three Cases of Erythema Multiforme Developed during Deflazacort Therapy in Children with Nephrotic Syndrome

Seung Jin Lee, Bong Hwa Kang, Min Hyun Cho

Department of Pediatrics, Kyungpook National University School of Medicine, Daegu, South Korea

Corresponding Author: Min Hyun Cho ,Tel: +82-53-200-2741, Fax: +82-53-200-2029, Email: chomh@knu.ac.kr

Received: May 27, 2014; Accepted: July 15, 2014.

ABSTRACT

Erythema multiforme (EM) is an acute mucocutaneous disorder involving the skin, mouth, eyes, and genital organs. It is classified into EM minor and EM major according to the involvement of the mucosal membrane. Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) belong to EM major. Compared to EM minor, SJS presents with more severe and progressive symptoms, and has a higher mortality rate. Corticosteroids are used in the treatment of EM. We report three cases of EM (two cases of EM minor and one case of SJS) that developed during treatment with oral corticosteroid (deflazacort; Calcort®) in children with nephrotic syndrome.

Key words: Erythema multiforme | Stevens-Johnson syndrome | Nephrotic syndrome | Deflazacort